In GLS assessment, what does a more negative value indicate about LV shortening and function?

In GLS assessment, what does a more negative value indicate about LV shortening and function?

• A. Worse LV function
• B. No change in function
• C. Greater LV shortening and better function
• D. Increased LV mass

Answer: (C)

Global longitudinal strain (GLS) measures how much the LV shortens along its long axis during systole. Since shortening makes the value negative, a more negative GLS means greater shortening of the myocardium, which reflects better systolic function. For example, a GLS around -20% is normal, while less negative values indicate impaired function. Increased LV mass isn’t what GLS directly measures. Therefore the more negative value indicates greater LV shortening and better function.

Global longitudinal strain (GLS) measures how much the LV shortens along its long axis during systole. Since shortening makes the value negative, a more negative GLS means greater shortening of the myocardium, which reflects better systolic function. For example, a GLS around -20% is normal, while less negative values indicate impaired function. Increased LV mass isn’t what GLS directly measures. Therefore the more negative value indicates greater LV shortening and better function.